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AIPMT Biology Syllabus

Unit : 1 The Living World

Nature and scope of Biology. Methods of Biology. Our place in the universe. Laws that govern the universe and life. Level of organization. Cause and effect relationship.

Being alive – what does it mean? Present approach to understand life processes; self duplication and survival; adaptation; death as a positive part of life. An attempt to define life in the above.

Origin of life and its maintenance. Origin and diversity of life. Physical and chemical principles that maintain life processes, the living crust and interdependence. The positive and negative aspects of progress in biological sciences. The future of the living world, identication of human responsibility in shaping our future.

Unit : 2. Unity of life

Cell as a unit of life. Small biomolecules; water, minerals, mono and oligosaccharides, lipids, amino acids, nucleotides and their chemistry. Cellular location and function. Macromolecules in cells-their chemistry, cellular location and functional significance. Polysaccharides, proteins and nucleic acids. Enzymes; chemical nature, classification, mechanism in action – enzyme complex, allosteric modulation (brief), irreversible activation. Biomembranes. Fluid mosaic model of membrane in transport recognition of external information (brief). Structural organization of the cell; light and electron microscopic views of cell, its organelles and their functions; Nucleus mitochondria, chloroplasts, endoplasmic reticulum. Golgi complex, Lysosomes, microtubules, cell wall, cilia and flagella, vacuoles, cell inclusions, A general account of cellular respiration. Fermentation, biological oxidation (A cycle outline), motochondrial electron transport chain, high energy bonds and oxidative phosphorylation, cell reproduction; Process of mitosis and meiosis.

Unit : 3 Diversity of Life

Introduction. The enormous variety of living things, the need for classification to cope with this variety; taxonomy and phylogeny; shortcoming of a two kingdom classification as plants and animals; a five kingdom classification. Monera, Protista, Plantae, Fungi and Animalia. The basic features of five kingdom classification; modes of obtaining nutrition-autotrophs and heterotrophs. Life styles : producers, consumers and decomposers, Unicellualarity and multicellularity phylogenetic relationships. Concepts of species, taxon and categries-hierarchical levels of classification; binomial nomenclature; principles of classification and nomenclature; identification and nature of viruses and bacteriophages and organisms. Kingdom Monera-archaebacteria-life in extreme environments: Bacteria, actinomycetes, Cyanobacteria, Examples to oillustrate autotrophic and heterotrophic life style; mineralizer-nitrogen fixers; Monera in cycling matter; symbiotic forms; disease producers. Kingdom Protista-Eucarytoic unicellular organisms; development of flagella and cilia; beginning of mitosis; syngamy and sex. Various life styles show in the major phyla. Evolutionary precursors of complex life forms. Diatoms, dinoflagellates, slime moulds, protozons; symbiotic forms. Plant kingdom-complex autotrophs, red brown and green algae; conquest of land bryophytes, ferns, gymnosperms and angiosperms. Vascularization: development of flower, fruit and seed. Kingdom fungi-lower fungi (Zygomycetes) higher fungi; (Ascomycetes animal kingdom-animal body pattern and symmetry. The development of body cavity in invertebarate vertebrate phyla. Salient feature with reference to habitat and example of phyla-porifera, coelenterata, helminthes, annelids, mollusca, arthopoda, echinoderms; chordata-(classes-fishes, amphibians, reptiles, birds and mammals) highlighting major characters.

Unit : 4 Organism and Environment

Species: Origin and concept of species population; interaction between environment and populations; community. Biotic community, interaction between different species, biotic stability, changes in the community-succession, Ecosystem; Interaction between biotic and abiotic components; major ecosystems, man made ecosystem-Agroecosystem Biosphere; flow of energy, trapping of solar energy, energy pathway, food chain, food web. Biogeochemical cycle, calcium and sulphur, ecological imbalance and its consequences. Conservation of natural resources; renewable and non-renewable (in brief). Water and land management , wasteland development. Wild life and forest conservation; causes for the extinction of some wild life, steps taken to conserve the remaining species, concept of endangered species-Indian examples, conservation of forest; Indian forests, kmportance of forests, hazards of deforestation, afforestation. Environmental pollution, sources, major pollutants of big cities of our country, their effects and methods of control, pollution due to nuclear fallout and waste disposal, effect and control, noise pollution; sources and effects.

Unit : 5 Multicellularity : Structure and Function – Plant Life

Form and function. Tissue system in flowering plants, meristematic and permanent. Minerals nutrition-essential elements, major functions of different elements, passive and active uptake to minerals. Modes of nutrition, transport of solutes and water in plants, Photosynthesis; photochemical and biosynthetic phases, diversity in photosynthetic pathways, photosynthetic electron transport and photophosphoryliation, photorespiration. Transpiration and exchange of gases. Stomatal mechanism. Osmoregulation in plants; water relations in plant cells, water potential. Reproduction and development in Angiosperms plants; asexual and sexual. Structure and functions of flower: development of male and female gemetophytes in angiosperms, pollination, fertilization and development of endosperm, embryo seed and fruit. Differentation and organ formation. Plant hormones and growth regulation; action of plant hormones in relation to seed dormancy and germination, apical dominance, senescence and abscission. Applications of synthetic growth regulators. A brief account of growth and movement in plants.

Unit : 6 Multicellularity : Structure of Function – Animal Life

Animal tissues, epithelial, connective, muscular, nerve. Animal nutrition; organs of digestion and digestive process, nutritional requirements for carbohydrates, proteins, fats, minerals and vitamins: nutritional imbalances and deficiency disease. Gas exchange and transport : Pulmonry gas exchange and organs involved, transport of gases in blood, gas exchange in aqueous media. Circulation : closed and open vascular systems, structure and pumping action of heat, arterial blood pressure, lymph. Excretion and osomoregulation. Ammonotelism, Ureotelism, urecotelism, urecotelism, excertion of water and urea with special reference to man. Role of kidney in regulation of plasma, osmolarity on the basis of nephron structure, skin and lungs in excretion. Hormonal coordination; hormones of mammals, role of hormones as messengers and regulators. Nervous coordination : central autonomic and peripheral nervous systems, receptors, effectors, reflex action, basic physiology of special senses, integrative control by neuroendocrinal systems. Locomotion; joints, muscle movements, types of skeletal muscles according to types of movement, basic aspects of human skelton. Reproduction : human reproduction. Female reproductive cycle. Embryonic development in mammals (upto three germs layers). Growth, repair and ageing.

Unit : 7 Heredity

Heredity and variation : Introduction, Mendel’s experiments with peas and idea of factors. Mendel’s law of inheritance. Genes : Packaging of heredity material in prokaryetes-bacterial chromosome; plasmid and eukaryote chromosomes. Extranuclear genes, viral genes. Linkage (genetic) maps. Sex determination and sex linkage. Genetic material and its replication, gene manipulation, Gene expression; genetic code, transcription, gene regulation. Molecular basis of differentiation.

Unit : 8 Origin and Evolution of Life

Origin of life : Living and non-living, chemical evolution, organic evolution; Oparin ideas, Miller – Urey experiments. Interrelationship among living organisms and evidences of evolution : fossilrecords including geological time scale, Morphological evidence – Hemology, vestigial organs, embryological similarities and biogeographical evidence.

Darwin’s two major contributions. Common origin of living organisms and recombination as sources of variability, selection acts upon variation, adaptation (Ledergerg’s replica plating experiment for indirect select of bacterial mutants). Reproductive isolation, sepeciation. Role of selection change of drift in determining composition of population. Selected examples : industrial melanism; drug resistance, mimicry, malaria in relation to G-6-PD deficiency and sickle cell disease. Human evolution : Palcontological evidence, man’s place among mammals. Brief idea of Dryopithecus, Australopithecus, home erectus, H. neadnderthlensis, Cromagnon man and sapiens. Human chromosomes, similarity in different racial groups. Comparison with chromosomes of nonhuman primates to indicate common origin ; Cultural vs. biological evolution.

Unit : 9 Applications of Biology

Introduction, Role of Biology in the amelioration of human problems. Domestication of plant-a historical account, improvement of crop plant; Principles of plant breeding and plant introduction. Use of fertilizers and economic and ecological aspects.

Use of pesticides : advantages and hazards. Biological methods of pest control. Crops today. Current concerns, gene pools and genetic conservation. Underutillized crops with potential uses of oilseeds, medicines, beverages, spices, fodder, New ceops-Leucaena (Subabul), Jojaba, Guayule, winged bean, etc. Biofertilisers-green manure, crop residues and nitrogen fixation (symbiotic, non symbiotic). Applications of tissue culture and genetic engineering in crops. Demestication and introduction of animals. Livestock, poultry, fisheries (fresh water, marine, aquaculture). Improvement of animals : principles of animal breeding. Major animal diseases and their control. Insects and their products (silk, honey, wax and Iac). Bioenergy-biomass, wood (combustion, gasification, ethanol). Cow dung cakes, gobar gas, plants as sources of hydrocarbons for producing petroleum, ethanol from starch and lignocellulose, Biotechnology, a brief historical account-manufacture of cheese. Youghurt, alcohol, alcohol, yeast, vitamins, organic acids, anti-biotics, steroids, dextrin’s, Scalling up laboratory findings to Industrial production. Production in insulin, human growth hormones, interferon. Communicable diseases including STD and diseases spread through ‘blood transfusion (hepatitis, AIDS, etc) Immune response, vaccines and antis era. Allergies and Inflammations. Inherited diseases and dysfunctions, sex – linked diseases, genetic incompatibilities, and genetic counselling. Cancer-major types., causes, diagnosis and treatment. Tissue and organ transplantation. Community health services and measures. Blood banks, Mental health, smoking, alcoholism and drug addiction-physiological symptoms and control measures. Industrial wastes, toxicology, pollution-related diseases. Biomedical engineering – spare parts for man, instruments for diagnosis of diseases and care. Human population related diseases. Human population growth problems and control, inequality between sexes – control measures; test – tube babies amniocentesis. Future of Biology.